Lion's Mane Mushrooms & Alzheimer's Disease
Hericium Erinaceus Mycelium & Alzheimer's TreatmentIn a 2018 study researchers noted its positive brain health benefits. For 30 days, they gave mice the fungus and noticed the following effects:
- Reducing glial cell activation
- Increasing insulin-degrading enzyme growth
- Promoting hippocampal neurogenesis
This study was especially interesting since it revealed three powerful benefits after just 30 days of the mice consuming the mushroom. Diminished glial cell activation slows cognitive decline. Hippocampal neurogenesis is a natural action in the brain that improves learning ability, mood and cognition. When the insulin-degrading enzyme is stimulated, it helps break down beta amyloid protein. As Dr. Alois Alzheimer discovered in 1906 after he dissected the brain of one of his patients, the plaques and tangles created by the beta amyloid protein contribute to cognitive decline.
A 2016 study showed that when the mushroom was enriched with erinacine A, it reduced plaque growth and raised the insulin-degrading enzyme levels in the bodies of lab mice after 30 days. Another 2016 study showed that the beneficial fungus had neuroprotective properties on the damaged brain cells of mice. A study that was conducted the same year also showed that erinacine A enrichment of the fungus had neuroprotective properties in mice. Additionally, a study found found that lion's mane consumption helped short-term memory in mice by preventing visual memory impairment. Visual learning is important in battling dementia and preserving cognitive abilities.
In 2009 study of 30 men and women diagnosed with mild cognitive impairment, where 15 people were given an extract of Hericium erinaceus. The others received a placebo, and researchers monitored everyone for 16 weeks. The placebo group scored lower on cognitive tests. About four weeks after the group that received the active substance stopped taking it, their cognitive test scores decreased. Indicating consistency was needed to maintain good results.
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